October 08, 2019 | Paris, France
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October 08, 2019
Paris, France
2èmes Journées du Club Anticorps de la SFI
08h30 - 09h15
Registration and welcome coffee

09h15 – 09h30

Welcome address - Renato Monteiro, SFI president

09h30 – 10h15

Christophe Blanchetot (Argen-X, The Nederlands)

Phage display technology for the generation of nanobodies

10h15 – 11h00

Margarida Gomes (Institut Pasteur, Paris)
High throughput selection of llama nanobodies against sGP protein of Ebola Virus using droplet-based microfluidics

Klervi Desrumeaux (Sanofi, Antony)
Which antibody source leads to success? A comparison study between immune, synthetic, and naive libraries for phage display antibody discovery

11h00 – 11h30

Break + B2B

11h30 - 12h10
Oral communications

Clément Nizak (ESPCI CNRS, Paris)
Parameters and determinants of responses to selection in antibody libraries


Jean-Christophe Rain (Hybrigenics services, Evry Génopôle)

In vitro selection, validation & optimization of synthetic single-domain antibodies for Tau

12h10 – 12h30

Flash poster presentations


Alexia Tavares Kanyavuz (INSERM U1138, Paris)
Heme as a modulator of the therapeutic efficacy of anti-cancer antibodies

Gabriel Aymé (Institut Pasteur, Paris)

Establishing An Automated Pipeline For Nanobodies Screening And Expression

Astrid Musnier (MAbSilico, Nouzilly)

In silico characterization of antibodies: A case study on an anti-CXCR4 nanobody

Melissa Sedkaoui (University of Technology of Compiègne)

scFv selection against endothelin receptors B by phage-display on whole cells


Coline Sivelle (CEA Saclay, Gif-sur-Yvette)
Dealing with immunogenicity: design of adalimumab mutants with reduced immunogenicity potential and increased activity

Thomas Secher (Université de Tours, Tours)
Immunogenicity of aerosolized monoclonal antibodies

12h30 – 14h00
Lunch (+ B2B)

14h00 – 14h45

Sally Ward (University of Southampton, United Kingdom)
Antibody engineering and functional targeting of the FcRn

14h45 - 15h25

Laurent Gauthier (Innate Pharma, Marseille)
Multifunctional natural killer cell engagers targeting NKp46 trigger protective tumor immunity

Angelina Mimoun (Centre de recherche des Cordeliers, Paris)
Towards the transplacental delivery of maternal FVIII to FVIII-deficient progeny for induction of active immune tolerance to therapeutic FVIII

15h25 – 15h45

Flash poster presentations


Myriam Nabhan (Inserm UMR-996, Châtenay-Malabry)
FcγRIIa-Syk axis controls human dendritic cells activation by infliximab aggregates and T cell response

Laurent Reber (ATIP Avenir team "Asthma, Allergy & Immunotherapy" CPTP, Toulouse

The anti-IgE antibody Omalizumab can induce adverse reactions through engagement of Fc gamma receptors

Maxime Moulard (BioCytex, Marseille)

Validation of a newly quantitative flow cytometry density assay to assess CD38 density in whole blood and bone marrow samples from multiple myeloma patients

Bernard Maillere (CEA, Gif sur Yvette)

Impact of pegylation and aggregation on T cell recognition of therapeutic antibodies

Coraline Borowczyk (CRMSB UMR5536, Bordeaux)

Autofluorescent intracellular NADH and FAD may be used to detect atheromatous plaque


Bénédicte Gagny (PROMEGA FRANCE, Charbonnières-Les-Bains)

Novel reporter-based bioassays for evaluating FcγR-dependent functions of therapeutic antibodies

15h45 – 16h15

Break + B2B

16h15 – 17h15 Oral communications

Meriem Bahri (CRCINA Inserm U1232, Nantes)
Rethinking anti-GD2 immunotherapeutic approaches to high-risk neuroblastoma

Philippe Mondon (LFB Biotechnologies, Courtaboeuf)

Dual targeting of FcRn and FcgRs via an innovative monomeric Fc fragment allows a superior inhibition of IgG dependent autoimmune pathologies


Ramdani Yanis (Groupe innovation et Ciblage Cellulaire, Tours)
Role of the neonatal Fc receptor in the pathophysiology of lupus

17h15 – 17h30

Concluding remarks - Hervé Watier, MAbImprove coordinator

Registration

Closed since October 07, 2019

Location

Institut IMAGINE, 24 bd du Montparnasse, 75015 Paris

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